Research Project: Using a biomarker of oocyte quality to improve embryo selection during assisted reproduction.

Principle Investigator: Dr. Lynne C. O'Shea

Funding: Merck Serono

​

The ability of an embryo to develop successfully greatly relies on the quality of the oocyte from which it has been generated.  Being able to accurately predetermine an embryo’s ability to provide a viable pregnancy prior to transfer remains a major obstacle to overcome in assisted reproduction. The identification of oocyte biological markers (biomarkers) indicative of a high quality embryo would allow for enhanced embryo selection techniques and improved clinical outcomes.

 

Discarded and donated-for-research follicular fluid, oocytes, granulosa cells and cumulus cells from routine human ART, will be analysed, while embryonic development and pregnancy will be the associated endpoints for developmental competence.

​

Want to get involved? Contact: lynne.oshea@ucd.ie

​

​

​